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Up to 20% of all epilepsy is suffered following a head injury. So research into new treatment which may prevent epilepsy after head injury could be an exciting breakthrough and human clinical trials may start in a few years.
Researchers found that a severe head injury disrupts the blood-brain barrier, so the blood protein albumin leaks into the brain, triggering inflammation which in turn can cause overexcited neurons and epileptic seizures. By blocking this cause, the drug can prevent seizures.
Daniela Kaufer, UC Berkeley associate professor of integrative biology said,
'This is the first-ever approach in which epilepsy development is stopped, as opposed to common drugs that try to prevent seizures once epilepsy develops.'
The research also explains for the first time how a brain injury caused by a blow to the head, stroke or infection causes epilepsy; by identifying the breach of the blood-brain barrier, the wall of cells lining the blood vessels in the brain.
At Head Injury UK, our specialist head injury solicitors welcome this development in our understanding of epilepsy and possibly how to treat it. Epilepsy following head injury often has long-term consequences on someone’s life, so any chance of preventing it following a head injury will significantly improve people’s lives in future. If you or a loved one has unfortunately suffered a head injury caused by someone else, please contact Ian Shovlin or call us on 0800 073 0988 to see how we can help you.
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